This is the very first retail tenant for the space, which for decades served as a residence.
This appears to be another unlicensed cannabis operation. (You can find a list of regulated, licensed dispensaries here.)
In August, the city put in place a new law to curb illegal stores:
Introduction 1001-B, now known as Local Law 107 of 2023, prohibits owners of commercial spaces from knowingly leasing to unlicensed sellers of marijuana or tobacco products, imposing fines of up to $10,000 on landlords for violations.
Steve Croman is the building's landlord. (A smoke shop is also on the way in one of his retail spaces on Avenue B.)
As previously noted, Anthony Pisano lived in this converted storefront full of antiques and whimsical curiosities for nearly 40 years. He died in 2018 at age 86. Check out some interior pics from his home here.