Plantworks has been around since 1974. In 2009, the Voice named it the city's Best Plant Shop:
The best mom-and-pop nursery in the city, it's packed with everything from common spider plants and bamboo to towering palms and Dracaena. The shop also sells an excellent selection of ceramic pots, seeds, fertilizers, and a noteworthy device called the Drip Drip, a ball that slowly releases drops of water onto your plant while you're away on vacation.
But in the new era of the Bowery, "mom and pop" might as well mean "doom and gloom." Across the street is where the controversial hotel project threatens the well-being of the Merchant's House Museum. This stretch of East Fourth Street includes the B Bar, the upscale housing at 2 Cooper Square and the boutique hotel Lafayette House.
The space has apparently been on the market for some time... the listing at RKF note that the "current tenant is month-to-month" on the lease. Also, "food not accepted." And 7-Eleven gets billing as a neighbor.
I asked the Plantworks folks if they were planning on moving. "Probably closing and not moving."